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» Risks with sleeping pills
» Benefits of stopping sleeping pills
» Guidelines & papers for stopping sleeping pills

Risks with sleeping pills

Topic
Title of the study
Year of publication
Cognitive problems
Association between use of benzodiazepines or related drugs and health, physical abilities and cognitive function: a non-randomised clinical study in the elderly
2017
Cognitive problems
Pharmacologic treatment of insomnia disorder: an evidence report for a clinical practice guideline by the american college of physicians
2016
Cognitive problems
Benzodiazepine misuse in the elderly: risk factors, consequences, and management
2016
Cognitive problems
Sedative hypnotics in older people with insomnia: meta-analysis of risk and benefits
2005
Death
Benzodiazepines and risk of death: results from two large cohort studies in france and uk
2015
Death
Is usage of hypnotics associated with mortality
2008
Death
Mortality hazard associated with prescription hypnotics
1998
Dementia
Review of safety and efficacy of sleep medicines in older adults
2016
Dementia
Benzodiazepine misuse in the elderly: risk factors, consequences, and management
2016
Dementia
Regular benzodiazepine and z-substance use and risk of dementia: an analysis of germal claim data
2016
Dementia
Risk of dementia in patients with insomnia and long-term use of hypnotics: a population-based retrospective cohort study
2012
Dementia
Is benzodiazepine use a risk factor for cognitive decline and dementia? A literature review of epidemiological studies
2005
Dependence & withdrawal
Benzodiazepine misuse in the elderly: risk factors, consequences, and management
2016
Dependence & withdrawal
Zopiclone: is there casue for concern in addiction services and general practice?
2014
Dependence & withdrawal
Benzodiazepines revisted—will we ever learn?
2011
Dependence & withdrawal
The prevalence of benzodiazepine dependence among community-dwelling older adults users in Quebec according to typical and atypcial criteria
2010
Dependence & withdrawal
Factors associated with benzodiazepine dependence among community-dwelling seniors
2009
Dependence & withdrawal
Evidence of zolpidem abuse and dependence: results of the French centre for evaluation and infromation on pharamcodependence (CEIP) network survey
2007
Dependence & withdrawal
Long-term therapeutic use of benzodiazepines. I. Effects of abrupt discontinuation
1990
Dependence & withdrawal
Benzodiazepine withdrawl syndrome: a literature review and evaluation
1982
Driving performance and accidents
Benzodiazepine misuse in the elderly: risk factors, consequences, and management
2016
Driving performance and accidents
Zopiclone’s residual effects on actual driving performance in a standardized test: a pooled analysis of age and sex effects in 4 placebo-controlled studies
2014
Driving performance and accidents
Zolpidem and zopiclone impair similarly monotonous driving performance after a single nightime intake in aged subkects
2011
Driving performance and accidents
Highway driving in the elderly the morning after bedtime use of hypnotics: a comparison between temazepam 20mg, zopiclone 7.5mg and placebo
2009
Driving performance and accidents
Road traffic accident risk related to prescriptions of the hypnotics zopiclone, zolpidem, flunitrazepam and nitrazepam
2008
Driving performance and accidents
Hypnotics and driving safety: meta-analysis of randomized controlled trials applying the on-the-road driving test
2006
Driving performance and accidents
Next-day residual effects of hypnotics in DSM=IV primary insomnia: a driving simulator study with simultaneous electroencephalogram monitoring
2005
Driving performance and accidents
A general model of the effects of sleep medications on the risk and cost of motor vehicle accidents and its application to France
2001
Drug interactions
Our other prescription drug problem (dangers of coprescribing benzodiazepines and opioids)
2018
Drug interactions
Risks, management, and monitoring of combination opioid, benzodiazepines, and/or alcohol use
2013
Drug interactions
Economic impact of inappropriate benzodiazepine prescribing and related drug interactions among elderly persons
2013
Falls & fractures
Benzodiazepine misuse in the elderly: risk factors, consquences and management
2016
Falls & fractures
Zolpidem is independently associated with increased risk of inpatient falls
2013
Falls & fractures
Nonbenzodiazepine sleep medication use and hip fractures in nursing home residents
2013
Falls & fractures
Risk of fractures requiring hospitalization after an initial prescription for zolpidem, alprazolam, lorazepam or diazepam in older adults
2011
Falls & fractures
Inappropriate benzodiazepine use in older adults and the risk of fracture
2008
Falls & fractures
The costs of benzodiazepine-associated hospital-treated fall injuries in the EU: a Pharmo study
2003
Loss of balance
Quantifying the magnitude of a risk for balance impairement on falls in community-dwelling older adults: a systematic review and meta-analysis
2010
Loss of balance
Effect of hypnotic drugs on body balance and standing steadiness
2010
Loss of balance
Postural instability and consequent falls and hip fractures associated with use of hypnotics in the elderly: a comparative review
2005
Pneumonia
The risk of pneumonia in older adults using nonbenzodiazepine hypnotics
2016
Pneumonia
The association between benzodiazepines and influenza-like illness-related pneumonia and mortality: a survival analysis using UK Primary Care data
2016
Pneumonia
Benzodiazepine misuse in the elderly: risk factors, consequences, and management
2016
Pneumonia
Meta-analysis of hypnotics and infections: eszopiclone, ramelteon, zapleplon and zolpidem
2009
Social isolation
Effect of fall-related concerns on physcial, mental and social function I community-dwelling older adults: a prospective cohort study
2014
Social isolation
Engagement in leisure activities and benzodiazepine use in French community-dwelling elderly population
2012

Benefits of stopping sleeping pills

Topic
Title of the study
Year of publication
Fewer falls
Withdrawal of fall risk-increasing drugs
2016
Improved strength and balance
Handgrip strength and balance in older adults following withdrawal from long-term use of temazepam, zopiclone or zolpidem as hypnotics
2014
Better cognitive functioning
Effects of discontinuing benzodiazepine-derivative hypnotics on postural sway and cognitive functions in the elderly
2010

Guidelines & papers for stopping sleeping pills

Source
Title of the guideline or study
Year of publication
Dalhousie University
Patient Self-Guided Interventions to Reduce Sedative Use and Improve Sleep: The YAWNS NB Randomized Clinical Trial
2024
Canadian Coalition for Seniors' Mental Health
Canadian Guidelines on Benzodiazepine Receptor Agonists Use Disorder Among Older Adults
2019
Bruyère Research Institute, Ottawa
Deprescribing benzodiazepine receptor agonists: evidence-based clinical practice guideline
2018
Dalhousie University
Deprescribing benzodiazepines and Z-drugs in community-dwelling adults: a scoping review
2015

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